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Elevated Cellular PD1/PD-L1 Expression Confers Acquired Resistance to Cisplatin in Small Cell Lung Cancer Cells

Although small cell lung cancer (SCLC) is highly responsive to chemotherapies (e.g., cisplatin-etoposide doublet), virtually almost all responsive SCLC patients experience disease recurrence characterized by drug resistance. The mechanisms underlying cisplatin resistance remain elusive. Here we repo...

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Detalles Bibliográficos
Autores principales: Yan, Fei, Pang, Jiuxia, Peng, Yong, Molina, Julian R., Yang, Ping, Liu, Shujun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017656/
https://www.ncbi.nlm.nih.gov/pubmed/27610620
http://dx.doi.org/10.1371/journal.pone.0162925