Novel Metabolic Abnormalities in the Tricarboxylic Acid Cycle in Peripheral Cells From Huntington’s Disease Patients

Metabolic dysfunction is well-documented in Huntington’s disease (HD). However, the link between the mutant huntingtin (mHTT) gene and the pathology is unknown. The tricarboxylic acid (TCA) cycle is the main metabolic pathway for the production of NADH for conversion to ATP via the electron transpor...

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Detalles Bibliográficos
Autores principales: Naseri, Nima N., Bonica, Joseph, Xu, Hui, Park, Larry C., Arjomand, Jamshid, Chen, Zhengming, Gibson, Gary E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017661/
https://www.ncbi.nlm.nih.gov/pubmed/27611087
http://dx.doi.org/10.1371/journal.pone.0160384

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017661/
https://www.ncbi.nlm.nih.gov/pubmed/27611087
http://dx.doi.org/10.1371/journal.pone.0160384

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