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Comprehensive Small RNA-Seq of Adeno-Associated Virus (AAV)-Infected Human Cells Detects Patterns of Novel, Non-Coding AAV RNAs in the Absence of Cellular miRNA Regulation

Most DNA viruses express small regulatory RNAs, which interfere with viral or cellular gene expression. For adeno-associated virus (AAV), a small ssDNA virus with a complex biphasic life cycle miRNAs or other small regulatory RNAs have not yet been described. This is the first comprehensive Illumina...

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Detalles Bibliográficos
Autores principales: Stutika, Catrin, Mietzsch, Mario, Gogol-Döring, Andreas, Weger, Stefan, Sohn, Madlen, Chen, Wei, Heilbronn, Regine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017669/
https://www.ncbi.nlm.nih.gov/pubmed/27611072
http://dx.doi.org/10.1371/journal.pone.0161454