The Neurite Outgrowth Inhibitory Nogo-A-Δ20 Region Is an Intrinsically Disordered Segment Harbouring Three Stretches with Helical Propensity

Functional recovery from central neurotrauma, such as spinal cord injury, is limited by myelin-associated inhibitory proteins. The most prominent example, Nogo-A, imposes an inhibitory cue for nerve fibre growth via two independent domains: Nogo-A-Δ20 (residues 544–725 of the rat Nogo-A sequence) an...

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Detalles Bibliográficos
Autores principales: Zelenay, Viviane, Arzt, Michael E., Bibow, Stefan, Schwab, Martin E., Riek, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017703/
https://www.ncbi.nlm.nih.gov/pubmed/27611089
http://dx.doi.org/10.1371/journal.pone.0161813

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017703/
https://www.ncbi.nlm.nih.gov/pubmed/27611089
http://dx.doi.org/10.1371/journal.pone.0161813

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