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A Novel Potential Positron Emission Tomography Imaging Agent for Vesicular Monoamine Transporter Type 2

In the early 1990s, 9-(+)-(11)C-dihydrotetrabenazine (9-(+)-(11)C-DTBZ) was shown to be a useful positron emission tomography (PET) imaging agent for various neurodegenerative disorders. Here, we described the radiosynthesis and evaluation of the 9-(+)-(11)C-DTBZ analog, 10-(+)-(11)C-DTBZ, as a vesi...

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Detalles Bibliográficos
Autores principales: Huang, Zih-Rou, Tsai, Chia-Ling, Huang, Ya-Yao, Shiue, Chyng-Yann, Tzen, Kai-Yuan, Yen, Ruoh-Fang, Hsin, Ling-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017712/
https://www.ncbi.nlm.nih.gov/pubmed/27612194
http://dx.doi.org/10.1371/journal.pone.0161295