Pfh1 Is an Accessory Replicative Helicase that Interacts with the Replisome to Facilitate Fork Progression and Preserve Genome Integrity

Replicative DNA helicases expose the two strands of the double helix to the replication apparatus, but accessory helicases are often needed to help forks move past naturally occurring hard-to-replicate sites, such as tightly bound proteins, RNA/DNA hybrids, and DNA secondary structures. Although the...

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Detalles Bibliográficos
Autores principales: McDonald, Karin R., Guise, Amanda J., Pourbozorgi-Langroudi, Parham, Cristea, Ileana M., Zakian, Virginia A., Capra, John A., Sabouri, Nasim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017727/
https://www.ncbi.nlm.nih.gov/pubmed/27611590
http://dx.doi.org/10.1371/journal.pgen.1006238

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017727/
https://www.ncbi.nlm.nih.gov/pubmed/27611590
http://dx.doi.org/10.1371/journal.pgen.1006238

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