The GSTM2 C-Terminal Domain Depresses Contractility and Ca(2+) Transients in Neonatal Rat Ventricular Cardiomyocytes

The cardiac ryanodine receptor (RyR2) is an intracellular ion channel that regulates Ca(2+) release from the sarcoplasmic reticulum (SR) during excitation–contraction coupling in the heart. The glutathione transferases (GSTs) are a family of phase II detoxification enzymes with additional functions...

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Detalles Bibliográficos
Autores principales: Hewawasam, Ruwani P., Liu, Dan, Casarotto, Marco G., Board, Philip G., Dulhunty, Angela F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017731/
https://www.ncbi.nlm.nih.gov/pubmed/27612301
http://dx.doi.org/10.1371/journal.pone.0162415

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017731/
https://www.ncbi.nlm.nih.gov/pubmed/27612301
http://dx.doi.org/10.1371/journal.pone.0162415

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