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The GSTM2 C-Terminal Domain Depresses Contractility and Ca(2+) Transients in Neonatal Rat Ventricular Cardiomyocytes
The cardiac ryanodine receptor (RyR2) is an intracellular ion channel that regulates Ca(2+) release from the sarcoplasmic reticulum (SR) during excitation–contraction coupling in the heart. The glutathione transferases (GSTs) are a family of phase II detoxification enzymes with additional functions...
Autores principales: | Hewawasam, Ruwani P., Liu, Dan, Casarotto, Marco G., Board, Philip G., Dulhunty, Angela F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017731/ https://www.ncbi.nlm.nih.gov/pubmed/27612301 http://dx.doi.org/10.1371/journal.pone.0162415 |
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