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Investigating the Effect of Ligand Amount and Injected Therapeutic Activity: A Simulation Study for (177)Lu-Labeled PSMA-Targeting Peptides

In molecular radiotherapy with (177)Lu-labeled prostate specific membrane antigen (PSMA) peptides, kidney and/or salivary glands doses limit the activity which can be administered. The aim of this work was to investigate the effect of the ligand amount and injected activity on the tumor-to-normal ti...

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Detalles Bibliográficos
Autores principales: Kletting, Peter, Schuchardt, Christiane, Kulkarni, Harshad R., Shahinfar, Mostafa, Singh, Aviral, Glatting, Gerhard, Baum, Richard P., Beer, Ambros J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017739/
https://www.ncbi.nlm.nih.gov/pubmed/27611841
http://dx.doi.org/10.1371/journal.pone.0162303