GenToS: Use of Orthologous Gene Information to Prioritize Signals from Human GWAS

Genome-wide association studies (GWAS) evaluate associations between genetic variants and a trait or disease of interest free of prior biological hypotheses. GWAS require stringent correction for multiple testing, with genome-wide significance typically defined as association p-value <5*10(−8). T...

Descripción completa

Detalles Bibliográficos
Autores principales: Hoppmann, Anselm S., Schlosser, Pascal, Backofen, Rolf, Lausch, Ekkehart, Köttgen, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017755/
https://www.ncbi.nlm.nih.gov/pubmed/27612175
http://dx.doi.org/10.1371/journal.pone.0162466

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017755/
https://www.ncbi.nlm.nih.gov/pubmed/27612175
http://dx.doi.org/10.1371/journal.pone.0162466

Ejemplares similares