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GenToS: Use of Orthologous Gene Information to Prioritize Signals from Human GWAS
Genome-wide association studies (GWAS) evaluate associations between genetic variants and a trait or disease of interest free of prior biological hypotheses. GWAS require stringent correction for multiple testing, with genome-wide significance typically defined as association p-value <5*10(−8). T...
Autores principales: | Hoppmann, Anselm S., Schlosser, Pascal, Backofen, Rolf, Lausch, Ekkehart, Köttgen, Anna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017755/ https://www.ncbi.nlm.nih.gov/pubmed/27612175 http://dx.doi.org/10.1371/journal.pone.0162466 |
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