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Peroral Estradiol Is Sufficient to Induce Carcinogen-Induced Mammary Tumorigenesis in Ovariectomized Rats without Progesterone

A role for estrogens in breast cancer is widely accepted, however, recent evidence highlights that timing and exposure levels are important in determining whether they elicit harmful versus beneficial effects. The rat chemical carcinogen model has been widely used to study the effects of estrogens b...

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Detalles Bibliográficos
Autores principales: Stires, Hillary, Saboya, Mariana, Globerman, Samantha P., Cohick, Wendie S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017759/
https://www.ncbi.nlm.nih.gov/pubmed/27611094
http://dx.doi.org/10.1371/journal.pone.0162662