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Peroral Estradiol Is Sufficient to Induce Carcinogen-Induced Mammary Tumorigenesis in Ovariectomized Rats without Progesterone
A role for estrogens in breast cancer is widely accepted, however, recent evidence highlights that timing and exposure levels are important in determining whether they elicit harmful versus beneficial effects. The rat chemical carcinogen model has been widely used to study the effects of estrogens b...
Autores principales: | Stires, Hillary, Saboya, Mariana, Globerman, Samantha P., Cohick, Wendie S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017759/ https://www.ncbi.nlm.nih.gov/pubmed/27611094 http://dx.doi.org/10.1371/journal.pone.0162662 |
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