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Enhanced binding of antibodies generated during chronic HIV infection to mucus component MUC16

Transmission of HIV across mucosal barriers accounts for the majority of HIV infections worldwide. Thus, efforts aimed at enhancing protective immunity at these sites are a top priority, including increasing virus-specific antibodies (Abs) and antiviral activity at mucosal sites. Mucin proteins, inc...

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Detalles Bibliográficos
Autores principales: Gunn, Bronwyn, Schneider, Jeffrey, Shansab, Maryam, Bastian, Arangassery Rosemary, Fahrbach, Kelly, Smith, Archer, Mahan, Alison, Karim, Marcus, Licht, Anna, Zvonar, Ivan, Tedesco, Jacquelynn, Anderson, Meegan, Chapel, Anais, Suscovich, Todd, Malaspina, David, Streeck, Hendrik, Walker, Bruce D., Kim, Arthur, Lauer, Georg, Altfeld, Marcus, Pillai, Shiv, Szleifer, Igal, Kelleher, Neil L., Kiser, Patrick F., Hope, Thomas J., Alter, Galit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017893/
https://www.ncbi.nlm.nih.gov/pubmed/26960182
http://dx.doi.org/10.1038/mi.2016.8