The Conundrum of Genetic “Drivers” in Benign Conditions

Advances in deep genomic sequencing have identified a spectrum of cancer-specific passenger and driver aberrations. Clones with driver anomalies are believed to be positively selected during carcinogenesis. Accumulating evidence, however, shows that genomic alterations, such as those in BRAF, RAS, E...

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Detalles Bibliográficos
Autores principales: Kato, Shumei, Lippman, Scott M., Flaherty, Keith T., Kurzrock, Razelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017937/
https://www.ncbi.nlm.nih.gov/pubmed/27059373
http://dx.doi.org/10.1093/jnci/djw036