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NHERF1/EBP50 Suppresses Wnt-β-Catenin Pathway–Driven Intestinal Neoplasia()

NHERF1/EBP50, an adaptor molecule that interacts with β-catenin, YAP, and PTEN, has been recently implicated in the progression of various human malignancies, including colorectal cancer. We report here that NHERF1 acts as a tumor suppressor in vivo for intestinal adenoma development. NHERF1 is high...

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Detalles Bibliográficos
Autores principales: Georgescu, Maria-Magdalena, Gagea, Mihai, Cote, Gilbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5018097/
https://www.ncbi.nlm.nih.gov/pubmed/27566107
http://dx.doi.org/10.1016/j.neo.2016.07.003