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Micro-Environmental Stress Induces Src-Dependent Activation of Invadopodia and Cell Migration in Ewing Sarcoma

Metastatic Ewing sarcoma has a very poor prognosis and therefore new investigations into the biologic drivers of metastatic progression are key to finding new therapeutic approaches. The tumor microenvironment is highly dynamic, leading to exposure of different regions of a growing solid tumor to ch...

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Detalles Bibliográficos
Autores principales: Bailey, Kelly M., Airik, Merlin, Krook, Melanie A., Pedersen, Elisabeth A., Lawlor, Elizabeth R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5018098/
https://www.ncbi.nlm.nih.gov/pubmed/27566104
http://dx.doi.org/10.1016/j.neo.2016.06.008