Structure-Based Prediction of Protein-Folding Transition Paths

We propose a general theory to describe the distribution of protein-folding transition paths. We show that transition paths follow a predictable sequence of high-free-energy transient states that are separated by free-energy barriers. Each transient state corresponds to the assembly of one or more d...

Descripción completa

Detalles Bibliográficos
Autores principales: Jacobs, William M., Shakhnovich, Eugene I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2016
Materias:
Proteins
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5018131/
https://www.ncbi.nlm.nih.gov/pubmed/27602721
http://dx.doi.org/10.1016/j.bpj.2016.06.031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5018131/
https://www.ncbi.nlm.nih.gov/pubmed/27602721
http://dx.doi.org/10.1016/j.bpj.2016.06.031

Ejemplares similares