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Structure-Based Prediction of Protein-Folding Transition Paths
We propose a general theory to describe the distribution of protein-folding transition paths. We show that transition paths follow a predictable sequence of high-free-energy transient states that are separated by free-energy barriers. Each transient state corresponds to the assembly of one or more d...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Biophysical Society
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5018131/ https://www.ncbi.nlm.nih.gov/pubmed/27602721 http://dx.doi.org/10.1016/j.bpj.2016.06.031 |