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β-Catenin signaling positively regulates glutamate uptake and metabolism in astrocytes

BACKGROUND: Neurological disorders have been linked to abnormal excitatory neurotransmission. Perturbations in glutamate cycling can have profound impacts on normal activity, lead to excitotoxicity and neuroinflammation, and induce and/or exacerbate impairments in these diseases. Astrocytes play a k...

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Detalles Bibliográficos
Autores principales: Lutgen, Victoria, Narasipura, Srinivas D., Sharma, Amit, Min, Stephanie, Al-Harthi, Lena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5018172/
https://www.ncbi.nlm.nih.gov/pubmed/27612942
http://dx.doi.org/10.1186/s12974-016-0691-7