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Pax6 associates with H3K4-specific histone methyltransferases Mll1, Mll2, and Set1a and regulates H3K4 methylation at promoters and enhancers

BACKGROUND: Pax6 is a key regulator of the entire cascade of ocular lens formation through specific binding to promoters and enhancers of batteries of target genes. The promoters and enhancers communicate with each other through DNA looping mediated by multiple protein–DNA and protein–protein intera...

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Detalles Bibliográficos
Autores principales: Sun, Jian, Zhao, Yilin, McGreal, Rebecca, Cohen-Tayar, Yamit, Rockowitz, Shira, Wilczek, Carola, Ashery-Padan, Ruth, Shechter, David, Zheng, Deyou, Cvekl, Ales
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5018195/
https://www.ncbi.nlm.nih.gov/pubmed/27617035
http://dx.doi.org/10.1186/s13072-016-0087-z