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Cryo-electron microscopy structure of a coronavirus spike glycoprotein trimer

The tremendous pandemic potential of coronaviruses was demonstrated twice in the past few decades by two global outbreaks of deadly pneumonia. Entry of coronaviruses into cells is mediated by the transmembrane spike glycoprotein S, which forms a trimer carrying receptor-binding and membrane fusion f...

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Detalles Bibliográficos
Autores principales: Walls, Alexandra C., Tortorici, M. Alejandra, Bosch, Berend-Jan, Frenz, Brandon, Rottier, Peter J. M., DiMaio, Frank, Rey, Félix A., Veesler, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5018210/
https://www.ncbi.nlm.nih.gov/pubmed/26855426
http://dx.doi.org/10.1038/nature16988