QSAR Analysis for Some 1, 2-Benzisothiazol-3-one Derivatives as Caspase-3 Inhibitors by Stepwise MLR Method

Caspase-3 inhibitory activities of some 1, 2-benzisothiazol-3-one derivatives were modeled by quantitative structure–activity relationship (QSAR) using stepwise-multiple linear regression (SW-MLR) method. The built model was robust and predictive with correlation coefficient (R(2)) of 0.91 and 0.59...

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Detalles Bibliográficos
Autores principales: Hajimahdi, Zahra, Safizadeh, Fatemeh, Zarghi, Afshin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5018271/
https://www.ncbi.nlm.nih.gov/pubmed/27642314

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5018271/
https://www.ncbi.nlm.nih.gov/pubmed/27642314

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