Diazoxide Attenuates Postresuscitation Brain Injury in a Rat Model of Asphyxial Cardiac Arrest by Opening Mitochondrial ATP-Sensitive Potassium Channels

Objective. We investigated whether and how diazoxide can attenuate brain injury after cardiopulmonary resuscitation (CPR) by selective opening of mitochondrial ATP-sensitive potassium (mitoKATP) channels. Methods. Adult male Sprague-Dawley rats with induced cerebral ischemia (n = 10 per group) recei...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Haidong, Wang, Peng, Li, Yi, Wu, Manhui, Lin, Jiali, Huang, Zitong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5018309/
https://www.ncbi.nlm.nih.gov/pubmed/27648441
http://dx.doi.org/10.1155/2016/1253842

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5018309/
https://www.ncbi.nlm.nih.gov/pubmed/27648441
http://dx.doi.org/10.1155/2016/1253842

Ejemplares similares