Impacts of the G145R Mutation on the Structure and Immunogenic Activity of the Hepatitis B Surface Antigen: A Computational Analysis

BACKGROUND: Vaccine-escaped hepatitis B virus (HBV) mutations occur within the “a” determinant area, which is located in the major hydrophilic region (MHR) of the hepatitis B surface antigen (HBsAg) protein. It is now well established that the common G145R mutation is highly capable of escaping from...

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Detalles Bibliográficos
Autores principales: Rezaee, Reza, Poorebrahim, Mansour, Najafi, Saeideh, Sadeghi, Solmaz, Pourdast, Alieh, Alavian, Seyed Moayed, Alavian, Seyed Ehsan, Poortahmasebi, Vahdat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Kowsar 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5018363/
https://www.ncbi.nlm.nih.gov/pubmed/27642350
http://dx.doi.org/10.5812/hepatmon.39097

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5018363/
https://www.ncbi.nlm.nih.gov/pubmed/27642350
http://dx.doi.org/10.5812/hepatmon.39097

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