Age‐dependent effects of APOE ε4 in preclinical Alzheimer's disease

OBJECTIVE: The ε4 allele of apolipoprotein E (APOE) is the strongest known common genetic risk factor for Alzheimer's disease (AD) and alters age of onset in retrospective studies. Here, we longitudinally test the effects of APOE ε4 genotype and age during progression from normal cognition to A...

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Detalles Bibliográficos
Autores principales: Bonham, Luke W., Geier, Ethan G., Fan, Chun C., Leong, Josiah K., Besser, Lilah, Kukull, Walter A., Kornak, John, Andreassen, Ole A., Schellenberg, Gerard D., Rosen, Howard J., Dillon, William P., Hess, Christopher P., Miller, Bruce L., Dale, Anders M., Desikan, Rahul S., Yokoyama, Jennifer S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5018579/
https://www.ncbi.nlm.nih.gov/pubmed/27648456
http://dx.doi.org/10.1002/acn3.333

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5018579/
https://www.ncbi.nlm.nih.gov/pubmed/27648456
http://dx.doi.org/10.1002/acn3.333

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