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Pamidronate Down-regulates Tumor Necrosis Factor-alpha Induced Matrix Metalloproteinases Expression in Human Intervertebral Disc Cells

BACKGROUND: N-containing bisphosphonates (BPs), such as pamidronate and risedronate, can inhibit osteoclastic function and reduce osteoclast number by inducing apoptotic cell death in osteoclasts. The aim of this study is to demonstrate the effect of pamidronate, second generation nitrogen-containin...

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Detalles Bibliográficos
Autores principales: Kang, Young-Mi, Hong, Seong-Hwan, Yang, Jae-Ho, Oh, Jin-Cheol, Park, Jin-Oh, Lee, Byung Ho, Lee, Sang-Yoon, Kim, Hak-Sun, Lee, Hwan-Mo, Moon, Seong-Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Bone and Mineral Research 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5018610/
https://www.ncbi.nlm.nih.gov/pubmed/27622181
http://dx.doi.org/10.11005/jbm.2016.23.3.165