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Pamidronate Down-regulates Tumor Necrosis Factor-alpha Induced Matrix Metalloproteinases Expression in Human Intervertebral Disc Cells
BACKGROUND: N-containing bisphosphonates (BPs), such as pamidronate and risedronate, can inhibit osteoclastic function and reduce osteoclast number by inducing apoptotic cell death in osteoclasts. The aim of this study is to demonstrate the effect of pamidronate, second generation nitrogen-containin...
Autores principales: | Kang, Young-Mi, Hong, Seong-Hwan, Yang, Jae-Ho, Oh, Jin-Cheol, Park, Jin-Oh, Lee, Byung Ho, Lee, Sang-Yoon, Kim, Hak-Sun, Lee, Hwan-Mo, Moon, Seong-Hwan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Society for Bone and Mineral Research
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5018610/ https://www.ncbi.nlm.nih.gov/pubmed/27622181 http://dx.doi.org/10.11005/jbm.2016.23.3.165 |
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