Cargando…

Sodium nitrite exerts an antihypertensive effect and improves endothelial function through activation of eNOS in the SHR

Sodium nitrite (NaNO(2)) induces relaxation in isolated arteries partly through an endothelium-dependent mechanism involving NO-eNOS-sGC-cGMP pathway. The present study was designed to investigate the effect of chronic NaNO(2) administration on arterial systolic blood pressure (SBP) and vascular fun...

Descripción completa

Detalles Bibliográficos
Autores principales: Ling, Wei Chih, Murugan, Dharmani Devi, Lau, Yeh Siang, Vanhoutte, Paul M., Mustafa, Mohd Rais
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5018809/
https://www.ncbi.nlm.nih.gov/pubmed/27616322
http://dx.doi.org/10.1038/srep33048