Cargando…

Sodium nitrite exerts an antihypertensive effect and improves endothelial function through activation of eNOS in the SHR

Sodium nitrite (NaNO(2)) induces relaxation in isolated arteries partly through an endothelium-dependent mechanism involving NO-eNOS-sGC-cGMP pathway. The present study was designed to investigate the effect of chronic NaNO(2) administration on arterial systolic blood pressure (SBP) and vascular fun...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ling, Wei Chih, Murugan, Dharmani Devi, Lau, Yeh Siang, Vanhoutte, Paul M., Mustafa, Mohd Rais
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5018809/ https://www.ncbi.nlm.nih.gov/pubmed/27616322 http://dx.doi.org/10.1038/srep33048

Ejemplares similares

Epigallocatechin gallate (EGCG) alleviates vascular dysfunction in angiotensin II-infused hypertensive mice by modulating oxidative stress and eNOS
por: Mohd Sabri, Nurul Aiza, et al.
Publicado: (2022)

Chronic treatment with paeonol improves endothelial function in mice through inhibition of endoplasmic reticulum stress-mediated oxidative stress
por: Choy, Ker Woon, et al.
Publicado: (2017)

Endothelium-Dependent Relaxation Effect of Apocynum venetum Leaf Extract via Src/PI3K/Akt Signalling Pathway
por: Lau, Yeh Siang, et al.
Publicado: (2015)

Correction: Angiotensin 1-7 Protects against Angiotensin II-Induced Endoplasmic Reticulum Stress and Endothelial Dysfunction via Mas Receptor
por: Murugan, Dharmani, et al.
Publicado: (2016)

Angiotensin 1-7 Protects against Angiotensin II-Induced Endoplasmic Reticulum Stress and Endothelial Dysfunction via Mas Receptor
por: Murugan, Dharmani, et al.
Publicado: (2015)

Boldine Ameliorates Vascular Oxidative Stress and Endothelial Dysfunction: Therapeutic Implication for Hypertension and Diabetes
por: Lau, Yeh Siiang, et al.
Publicado: (2015)

Reactive Oxygen Species-Induced Impairment of Endothelium-Dependent Relaxations in Rat Aortic Rings: Protection by Methanolic Extracts of Phoebe grandis
por: Yeh-Siang, Lau, et al.
Publicado: (2011)

Antihypertensive Effects of IGTGIPGIW Peptide Purified from Hippocampus abdominalis: p-eNOS and p-AKT Stimulation in EA.hy926 Cells and Lowering of Blood Pressure in SHR Model
por: Lee, Hyo-Geun, et al.
Publicado: (2022)

Molecular mechanisms underlying pharmacological stimulation of eNOS expression and eNOS activity
por: Li, Huige, et al.
Publicado: (2009)

Consistent antioxidant and antihypertensive effects of oral sodium nitrite in DOCA-salt hypertension
por: Amaral, Jefferson H., et al.
Publicado: (2015)

Antihypertensive Effect of Dietary β-Conglycinin in the Spontaneously Hypertensive Rat (SHR)
por: Kawabeta, Koji, et al.
Publicado: (2022)

Hypotensive effect of Gentiana floribunda is mediated through Ca(++) antagonism pathway
por: Khan, Arif-ullah, et al.
Publicado: (2012)

Heterozygous eNOS Deficient Mice as a Model to Examine the Effects of eNOS Haploinsufficiency on the Cerebral Circulation
por: Didion, Sean P.
Publicado: (2017)

mTOR contributes to endothelium-dependent vasorelaxation by promoting eNOS expression and preventing eNOS uncoupling
por: Wang, Yiying, et al.
Publicado: (2022)

Association of genetic polymorphisms of eNOS with glaucoma
por: Liao, Qiong, et al.
Publicado: (2011)

PKC-Dependent Phosphorylation of eNOS at T495 Regulates eNOS Coupling and Endothelial Barrier Function in Response to G(+) -Toxins
por: Chen, Feng, et al.
Publicado: (2014)

Endothelial NO Production Is Mandatory for Epigallocatechin-3-Gallate–induced Vasodilation: Results From eNOS Knockout (eNOS(−/−)) Mice
por: Lorenz, Mario, et al.
Publicado: (2015)

Ursolic acid prevents doxorubicin‐induced cardiac toxicity in mice through eNOS activation and inhibition of eNOS uncoupling
por: Mu, Haiman, et al.
Publicado: (2019)

Multiple inducers of endothelial NOS (eNOS) dysfunction in sickle cell disease
por: Hebbel, Robert P., et al.
Publicado: (2021)

Upregulation of iNOS and phosphorylated eNOS in the implantation‐induced blastocysts of mice
por: Seki, Misato, et al.
Publicado: (2023)

Effect of Hydrolyzed Bird’s Nest on β-Cell Function and Insulin Signaling in Type 2 Diabetic Mice
por: Choy, Ker Woon, et al.
Publicado: (2021)

Data on eNOS T786 and G894T polymorphisms and peripheral blood eNOS mRNA levels in Sickle Cell Disease
por: Armenis, Iakovos, et al.
Publicado: (2016)

Expression of eNOS in kidneys from hypertensive patients
por: Gu, Xin, et al.
Publicado: (2010)

Frequency of eNOS polymorphisms in the Colombian general population
por: Serrano, Norma C, et al.
Publicado: (2010)

Neurogranin regulates eNOS function and endothelial activation
por: Cheriyan, Vino T., et al.
Publicado: (2020)

Edible Bird’s Nest Protects Against Hyperglycemia-Induced Oxidative Stress and Endothelial Dysfunction
por: Murugan, Dharmani Devi, et al.
Publicado: (2020)

Flavonoids as Natural Anti-Inflammatory Agents Targeting Nuclear Factor-Kappa B (NFκB) Signaling in Cardiovascular Diseases: A Mini Review
por: Choy, Ker Woon, et al.
Publicado: (2019)

Nitric oxide–dependent Src activation and resultant caveolin-1 phosphorylation promote eNOS/caveolin-1 binding and eNOS inhibition
por: Chen, Zhenlong, et al.
Publicado: (2012)

Paternal eNOS deficiency in mice affects glucose homeostasis and liver glycogen in male offspring without inheritance of eNOS deficiency itself
por: Hocher, Berthold, et al.
Publicado: (2022)

Recipient iNOS but Not eNOS Deficiency Reduces Luminal Narrowing in Tracheal Allografts
por: Minamoto, Kanji, et al.
Publicado: (2002)

Sildenafil Ameliorates Gentamicin-Induced Nephrotoxicity in Rats: Role of iNOS and eNOS
por: Morsy, Mohamed A., et al.
Publicado: (2014)

Targeting mechanosensitive endothelial TXNDC5 to stabilize eNOS and reduce atherosclerosis in vivo
por: Yeh, Chih-Fan, et al.
Publicado: (2022)

Antioxidant resveratrol restores renal sodium transport regulation in SHR
por: Javkhedkar, Apurva A, et al.
Publicado: (2015)

Perthamide C Inhibits eNOS and iNOS Expression and Has Immunomodulating Activity In Vivo
por: Bucci, Mariarosaria, et al.
Publicado: (2013)

eNOS/iNOS and endoplasmic reticulum stress-induced apoptosis in the placentas of patients with preeclampsia
por: Du, L, et al.
Publicado: (2017)

mRNA expression and localization of bNOS, eNOS and iNOS in human cervix at preterm and term labour
por: Törnblom, Susanne Abelin, et al.
Publicado: (2005)

eNOS Activation by HDL Is Impaired in Genetic CETP Deficiency
por: Gomaraschi, Monica, et al.
Publicado: (2014)

eNOS Gene Variants and the Risk of Premature Myocardial Infarction
por: Zigra, Aggeliki-Maria, et al.
Publicado: (2013)

eNOS Gene Variant in Patients with Coronary Artery Disease
por: Abolhalaj, Milad, et al.
Publicado: (2013)

Association of endothelial nitric oxide synthase (eNOS) gene polymorphisms and physical fitness levels with plasma nitrite concentrations and arterial blood pressure values in older adults
por: da Silva, Roberta Fernanda, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_821lakc6h3i5el1qvk8pbljh5k