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Effect of X-ray irradiation on ancient DNA in sub-fossil bones – Guidelines for safe X-ray imaging

Sub-fossilised remains may still contain highly degraded ancient DNA (aDNA) useful for palaeogenetic investigations. Whether X-ray computed [micro-] tomography ([μ]CT) imaging of these fossils may further damage aDNA remains debated. Although the effect of X-ray on DNA in living organisms is well do...

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Detalles Bibliográficos
Autores principales: Immel, Alexander, Le Cabec, Adeline, Bonazzi, Marion, Herbig, Alexander, Temming, Heiko, Schuenemann, Verena J., Bos, Kirsten I., Langbein, Frauke, Harvati, Katerina, Bridault, Anne, Pion, Gilbert, Julien, Marie-Anne, Krotova, Oleksandra, Conard, Nicholas J., Münzel, Susanne C., Drucker, Dorothée G., Viola, Bence, Hublin, Jean-Jacques, Tafforeau, Paul, Krause, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5018823/
https://www.ncbi.nlm.nih.gov/pubmed/27615365
http://dx.doi.org/10.1038/srep32969