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Akting up in the GABA hypothesis of schizophrenia: Akt1 deficiency modulates GABAergic functions and hippocampus-dependent functions
Accumulating evidence implies that both AKT1 and GABA(A) receptor (GABA(A)R) subunit genes are involved in schizophrenia pathogenesis. Activated Akt promotes GABAergic neuron differentiation and increases GABA(A)R expression on the plasma membrane. To elucidate the role of Akt1 in modulating GABAerg...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5018883/ https://www.ncbi.nlm.nih.gov/pubmed/27615800 http://dx.doi.org/10.1038/srep33095 |