Resistance mechanism of human immunodeficiency virus type-1 protease to inhibitors: A molecular dynamic approach

Human immunodeficiency virus type 1 (HIV-1) protease inhibitors comprise an important class of drugs used in HIV treatments. However, mutations of protease genes accelerated by low fidelity of reverse transcriptase yield drug resistant mutants of reduced affinities for the inhibitors. This problem i...

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Detalles Bibliográficos
Autores principales: Dayer, Mohammad Reza, Dayer, Mohammad Saaid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shiraz University 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5019311/
https://www.ncbi.nlm.nih.gov/pubmed/27843989

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5019311/
https://www.ncbi.nlm.nih.gov/pubmed/27843989

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