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In situ delivery of thermosensitive gel-mediated 5-fluorouracil microemulsion for the treatment of colorectal cancer

In situ administration of 5-fluorouracil (5FU) “thermosensitive” gel effectively reduced systemic side effects in treating colon rectal cancer; however, the penetration efficacy of the formulation was considerably low due to the poor lipid solubility of 5FU. The aim of this study was to develop ther...

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Detalles Bibliográficos
Autores principales: Wang, Lu-Lu, Huang, Shuai, Guo, Hui-Hui, Han, Yan-Xing, Zheng, Wen-Sheng, Jiang, Jian-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5019315/
https://www.ncbi.nlm.nih.gov/pubmed/27660416
http://dx.doi.org/10.2147/DDDT.S111351