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Preparation of novel pirfenidone microspheres for lung-targeted delivery: in vitro and in vivo study
The aim of this study was to develop and characterize pirfenidone (PF)-loaded chitosan microspheres for lung targeting. The microspheres were prepared using the emulsion-solvent evaporation method and characterized by assessing morphology, particle size, and zeta potential. The microspheres had a sp...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5019316/ https://www.ncbi.nlm.nih.gov/pubmed/27660413 http://dx.doi.org/10.2147/DDDT.S113670 |