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Intranasal administration of elastin-like polypeptide for therapeutic delivery to the central nervous system
Bypassing the blood–brain barrier is one of the primary considerations when designing compounds intended to function in the central nervous system (CNS). Intranasal (IN) administration of otherwise blood–brain barrier impermeable molecules can result in high CNS concentrations and low systemic accum...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5019317/ https://www.ncbi.nlm.nih.gov/pubmed/27660412 http://dx.doi.org/10.2147/DDDT.S106216 |