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Intranasal administration of elastin-like polypeptide for therapeutic delivery to the central nervous system

Bypassing the blood–brain barrier is one of the primary considerations when designing compounds intended to function in the central nervous system (CNS). Intranasal (IN) administration of otherwise blood–brain barrier impermeable molecules can result in high CNS concentrations and low systemic accum...

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Detalles Bibliográficos
Autores principales: McGowan, Jeremy WD, Shao, Qingmei, Vig, Parminder JS, Bidwell, Gene L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5019317/
https://www.ncbi.nlm.nih.gov/pubmed/27660412
http://dx.doi.org/10.2147/DDDT.S106216