Cargando…

Intranasal administration of elastin-like polypeptide for therapeutic delivery to the central nervous system

Bypassing the blood–brain barrier is one of the primary considerations when designing compounds intended to function in the central nervous system (CNS). Intranasal (IN) administration of otherwise blood–brain barrier impermeable molecules can result in high CNS concentrations and low systemic accum...

Descripción completa

Detalles Bibliográficos
Autores principales:	McGowan, Jeremy WD, Shao, Qingmei, Vig, Parminder JS, Bidwell, Gene L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2016
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5019317/ https://www.ncbi.nlm.nih.gov/pubmed/27660412 http://dx.doi.org/10.2147/DDDT.S106216

Ejemplares similares

Elastin-like polypeptide delivery of anti-inflammatory peptides to the brain following ischemic stroke
por: Howell, John Aaron, et al.
Publicado: (2023)

Molecular Size Modulates Pharmacokinetics, Biodistribution, and Renal Deposition of the Drug Delivery Biopolymer Elastin-like Polypeptide
por: Kuna, Marija, et al.
Publicado: (2018)

Intranasal Administration for Pain: Oxytocin and Other Polypeptides
por: Bharadwaj, Vimala N., et al.
Publicado: (2021)

Evaluation of Elastin-Like Polypeptides for Tumor Targeted Delivery of Doxorubicin to Glioblastoma
por: Dragojevic, Sonja, et al.
Publicado: (2019)

Development of elastin-like polypeptide for targeted specific gene delivery in vivo
por: Yi, Aena, et al.
Publicado: (2020)

Intracellular Delivery of Rapamycin From FKBP Elastin-Like Polypeptides Is Consistent With Macropinocytosis
por: Peddi, Santosh, et al.
Publicado: (2018)

The construction of elastin-like polypeptides and their applications in drug delivery system and tissue repair
por: Guo, Yingshu, et al.
Publicado: (2023)

Application of Elastin-like Polypeptide in Tumor Therapy
por: Shi, Xianggang, et al.
Publicado: (2022)

Circumventing Doxorubicin Resistance Using Elastin-like Polypeptide Biopolymer-Mediated Drug Delivery
por: Dragojevic, Sonja, et al.
Publicado: (2022)

Secreted production of an elastin-like polypeptide by Pichia pastoris
por: Schipperus, Roelof, et al.
Publicado: (2009)

Elastin-Derived Peptides in the Central Nervous System: Friend or Foe
por: Szychowski, Konrad A., et al.
Publicado: (2021)

Evaluation of Recent Intranasal Drug Delivery Systems to the Central Nervous System
por: Crowe, Tyler P., et al.
Publicado: (2022)

Application of bioengineered elastin-like polypeptide-based system for targeted gene delivery in tumor cells()
por: Yi, Aena, et al.
Publicado: (2022)

Solvent Properties of Water in Aqueous Solutions of Elastin-Like Polypeptide
por: Ferreira, Luisa A., et al.
Publicado: (2015)

pH-Responsive Elastin-Like Polypeptide Designer Condensates
por: de Haas, Robbert J., et al.
Publicado: (2023)

Advances and Challenges in Intranasal Delivery of Antipsychotic Agents Targeting the Central Nervous System
por: Pandey, Manisha, et al.
Publicado: (2022)

Editorial: Intranasal Delivery of Central Nervous System Active Drugs: Opportunities and Challenges
por: Rodrigues, Márcio, et al.
Publicado: (2022)

Central Nervous System Delivery of Antibodies and Their Single-Domain Antibodies and Variable Fragment Derivatives with Focus on Intranasal Nose to Brain Administration
por: Soleimanizadeh, Arghavan, et al.
Publicado: (2021)

Application of Bld-1-Embedded Elastin-Like Polypeptides in Tumor Targeting
por: Sarangthem, Vijaya, et al.
Publicado: (2018)

Proline Isomerization Regulates the Phase Behavior of Elastin-Like Polypeptides in Water
por: Zhao, Yani, et al.
Publicado: (2021)

Refining the Design of Diblock Elastin-Like Polypeptides for Self-Assembly into Nanoparticles
por: Dai, Michèle, et al.
Publicado: (2021)

Self-Assembly of Elastin-like Polypeptide Brushes on Silica Surfaces and Nanoparticles
por: Alvisi, Nicolò, et al.
Publicado: (2021)

Engineered elastin-like polypeptides: An efficient platform for enhanced cancer treatment
por: Jiang, Aiguo, et al.
Publicado: (2023)

Maternally sequestered therapeutic polypeptides – a new approach for the management of preeclampsia
por: Bidwell, Gene L., et al.
Publicado: (2014)

An improved nonchromatographic method for the purification of recombinant proteins using elastin-like polypeptide-tagged proteases
por: Lan, Dongming, et al.
Publicado: (2011)

Induction of protein body formation in plant leaves by elastin-like polypeptide fusions
por: Conley, Andrew J, et al.
Publicado: (2009)

Targeting prostate cancer cells with hybrid elastin-like polypeptide/liposome nanoparticles
por: Zhang, Wei, et al.
Publicado: (2018)

Improvement of physical properties of calcium phosphate cement by elastin-like polypeptide supplementation
por: Jang, Ji-Hyun, et al.
Publicado: (2018)

Thermally-Responsive Loading and Release of Elastin-Like Polypeptides from Contact Lenses
por: Wang, Wan, et al.
Publicado: (2019)

Improvement of the Bonding Properties of Mineral Trioxide Aggregate by Elastin-Like Polypeptide Supplementation
por: Kim, Hyun-Jung, et al.
Publicado: (2019)

Fibrillar Self-Assembly of a Chimeric Elastin-Resilin Inspired Engineered Polypeptide
por: Bracalello, Angelo, et al.
Publicado: (2019)

Engineering elastic sealants based on gelatin and elastin‐like polypeptides for endovascular anastomosis
por: Unal, Gokberk, et al.
Publicado: (2021)

Elastin-like Polypeptide Hydrogels for Tunable, Sustained Local Chemotherapy in Malignant Glioma
por: Dragojevic, Sonja, et al.
Publicado: (2022)

Solution behavior and encapsulation properties of fatty acid–elastin-like polypeptide conjugates
por: Zhang, Tingting, et al.
Publicado: (2023)

Establishment of an Olfactory Region-specific Intranasal Delivery Technique in Mice to Target the Central Nervous System
por: Flamm, Johannes, et al.
Publicado: (2022)

Intranasal Treatment of Central Nervous System Dysfunction in Humans
por: Chapman, Colin D., et al.
Publicado: (2012)

Surface and adsorption characteristics of three elastin-like polypeptide coatings with varying sequence lengths
por: Srokowski, Elizabeth M., et al.
Publicado: (2012)

Influence of Elastin-Like Polypeptide and Hydrophobin on Recombinant Hemagglutinin Accumulations in Transgenic Tobacco Plants
por: Phan, Hoang Trong, et al.
Publicado: (2014)

Elastin-like polypeptides as a promising family of genetically-engineered protein based polymers
por: Kowalczyk, Tomasz, et al.
Publicado: (2014)

Construction and Application of Elastin Like Polypeptide Containing IL-4 Receptor Targeting Peptide
por: Sarangthem, Vijaya, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_lugmgmevlsrrrkf2ilb26508ud