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A Computational Model for Predicting RNase H Domain of Retrovirus

RNase H (RNH) is a pivotal domain in retrovirus to cleave the DNA-RNA hybrid for continuing retroviral replication. The crucial role indicates that RNH is a promising drug target for therapeutic intervention. However, annotated RNHs in UniProtKB database have still been insufficient for a good under...

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Detalles Bibliográficos
Autores principales: Wu, Sijia, Zhang, Xinman, Han, Jiuqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5019361/
https://www.ncbi.nlm.nih.gov/pubmed/27574780
http://dx.doi.org/10.1371/journal.pone.0161913