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A Computational Model for Predicting RNase H Domain of Retrovirus
RNase H (RNH) is a pivotal domain in retrovirus to cleave the DNA-RNA hybrid for continuing retroviral replication. The crucial role indicates that RNH is a promising drug target for therapeutic intervention. However, annotated RNHs in UniProtKB database have still been insufficient for a good under...
Autores principales: | Wu, Sijia, Zhang, Xinman, Han, Jiuqiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5019361/ https://www.ncbi.nlm.nih.gov/pubmed/27574780 http://dx.doi.org/10.1371/journal.pone.0161913 |
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