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24R,25-Dihydroxyvitamin D3 Protects against Articular Cartilage Damage following Anterior Cruciate Ligament Transection in Male Rats

Osteoarthritis (OA) in humans is associated with low circulating 25-hydroxyvitamin D3 [25(OH)D(3)]. In vitamin D replete rats, radiolabeled 24R,25-dihydroxyvitamin D3 [24R,25(OH)(2)D(3)] accumulates in articular cartilage following injection of [(3)H]-25(OH)D(3). Previously, we showed that 24R,25(OH...

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Detalles Bibliográficos
Autores principales: Boyan, Barbara D., Hyzy, Sharon L., Pan, Qingfen, Scott, Kayla M., Coutts, Richard D., Healey, Robert, Schwartz, Zvi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5019362/
https://www.ncbi.nlm.nih.gov/pubmed/27575371
http://dx.doi.org/10.1371/journal.pone.0161782