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Histone Deacetylase Inhibition Restores Retinal Pigment Epithelium Function in Hyperglycemia

In diabetic individuals, macular edema is a major cause of vision loss. This condition is refractory to insulin therapy and has been attributed to metabolic memory. The retinal pigment epithelium (RPE) is central to maintaining fluid balance in the retina, and this function is compromised by the act...

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Detalles Bibliográficos
Autores principales: Desjardins, Danielle, Liu, Yueying, Crosson, Craig E., Ablonczy, Zsolt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5019386/
https://www.ncbi.nlm.nih.gov/pubmed/27617745
http://dx.doi.org/10.1371/journal.pone.0162596