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Histone Deacetylase Inhibition Restores Retinal Pigment Epithelium Function in Hyperglycemia
In diabetic individuals, macular edema is a major cause of vision loss. This condition is refractory to insulin therapy and has been attributed to metabolic memory. The retinal pigment epithelium (RPE) is central to maintaining fluid balance in the retina, and this function is compromised by the act...
Autores principales: | Desjardins, Danielle, Liu, Yueying, Crosson, Craig E., Ablonczy, Zsolt |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5019386/ https://www.ncbi.nlm.nih.gov/pubmed/27617745 http://dx.doi.org/10.1371/journal.pone.0162596 |
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