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Patients’ safety: is there a systemic release of gentamicin by gentamicin-coated tibia nails in clinical use?

INTRODUCTION: Osteitis is one of the most serious complications in orthopedic surgery. Expert Tibia Nail (ETN) PROtect™ coated with a biodegradable layer of gentamicin-laden polymer was developed for prophylaxis of osteomyelitis. In systemic administration, gentamicin has only a small therapeutic in...

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Detalles Bibliográficos
Autores principales: Moghaddam, Arash, Graeser, Viola, Westhauser, Fabian, Dapunt, Ulrike, Kamradt, Till, Woerner, Stefan M, Schmidmaier, Gerhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5019425/
https://www.ncbi.nlm.nih.gov/pubmed/27660456
http://dx.doi.org/10.2147/TCRM.S107398