Cargando…

Angiopoetin-2 Signals Do Not Mediate the Hypervascularization of Islets in Type 2 Diabetes

AIMS: Changes in the islet vasculature have been implicated in the regulation of β-cell survival and function during the progression to type 2 diabetes (T2D). Failure of the β-cell to compensate for the increased insulin demand in obesity eventually leads to diabetes; as a result of the complex inte...

Descripción completa

Detalles Bibliográficos
Autores principales: Shah, Payal, Lueschen, Navina, Ardestani, Amin, Oberholzer, Jose, Olerud, Johan, Carlsson, Per-Ola, Maedler, Kathrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5019443/
https://www.ncbi.nlm.nih.gov/pubmed/27617438
http://dx.doi.org/10.1371/journal.pone.0161834