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PDGF-BB Promotes Type I IFN-Dependent Vascular Alterations and Monocyte Recruitment in a Model of Dermal Fibrosis

Systemic sclerosis (SSc) is a chronic autoimmune disorder that can result in extensive tissue damage in the skin and, in advanced cases, internal organs. Vasculopathy, aberrant immune activation, and tissue fibrosis are three hallmarks of the disease that have been identified, with vasculopathy and...

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Detalles Bibliográficos
Autores principales: Cho, John S., Fang, Terry C., Reynolds, Taylor L., Sofia, Daniel J., Hamann, Stefan, Burkly, Linda C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5019454/
https://www.ncbi.nlm.nih.gov/pubmed/27618690
http://dx.doi.org/10.1371/journal.pone.0162758