Macrophage Depletion Attenuates Extracellular Matrix Deposition and Ductular Reaction in a Mouse Model of Chronic Cholangiopathies

Chronic cholangiopathies, such as primary and secondary sclerosing cholangitis, are progressive disease entities, associated with periportal accumulation of inflammatory cells, encompassing monocytes and macrophages, peribiliary extracellular matrix (ECM) deposition and ductular reaction (DR). This...

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Detalles Bibliográficos
Autores principales: Best, Jan, Verhulst, Stefaan, Syn, Wing-Kin, Lagaisse, Kimberly, van Hul, Noemi, Heindryckx, Femke, Sowa, Jan-Peter, Peeters, Liesbeth, Van Vlierberghe, Hans, Leclercq, Isabelle A., Canbay, Ali, Dollé, Laurent, van Grunsven, Leo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5019458/
https://www.ncbi.nlm.nih.gov/pubmed/27618307
http://dx.doi.org/10.1371/journal.pone.0162286

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5019458/
https://www.ncbi.nlm.nih.gov/pubmed/27618307
http://dx.doi.org/10.1371/journal.pone.0162286

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