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Tanshinone IIA Modulates Low Density Lipoprotein Uptake via Down-Regulation of PCSK9 Gene Expression in HepG2 Cells

Tanshinone IIA, one of the most pharmacologically bioactive phytochemicals isolated from Salvia miltiorrhiza Bunge, possesses several biological activities such as anti-inflammation, anti-cancer, neuroprotection and hypolipidemic activities. In this study, we aim to investigate the hypocholesterolem...

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Detalles Bibliográficos
Autores principales: Chen, Hung-Chen, Chen, Pei-Yi, Wu, Ming-Jiuan, Tai, Mi-Hsueh, Yen, Jui-Hung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5019481/
https://www.ncbi.nlm.nih.gov/pubmed/27617748
http://dx.doi.org/10.1371/journal.pone.0162414