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Tanshinone IIA Modulates Low Density Lipoprotein Uptake via Down-Regulation of PCSK9 Gene Expression in HepG2 Cells
Tanshinone IIA, one of the most pharmacologically bioactive phytochemicals isolated from Salvia miltiorrhiza Bunge, possesses several biological activities such as anti-inflammation, anti-cancer, neuroprotection and hypolipidemic activities. In this study, we aim to investigate the hypocholesterolem...
Autores principales: | Chen, Hung-Chen, Chen, Pei-Yi, Wu, Ming-Jiuan, Tai, Mi-Hsueh, Yen, Jui-Hung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5019481/ https://www.ncbi.nlm.nih.gov/pubmed/27617748 http://dx.doi.org/10.1371/journal.pone.0162414 |
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