Rewiring MAP kinases in Saccharomyces cerevisiae to regulate novel targets through ubiquitination
Evolution has often copied and repurposed the mitogen-activated protein kinase (MAPK) signaling module. Understanding how connections form during evolution, in disease and across individuals requires knowledge of the basic tenets that govern kinase-substrate interactions. We identify criteria suffic...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5019841/ https://www.ncbi.nlm.nih.gov/pubmed/27525484 http://dx.doi.org/10.7554/eLife.15200 |