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Alterations in Red Blood Cell Functionality Induced by an Indole Scaffold Containing a Y-Iminodiketo Moiety: Potential Antiproliferative Conditions

We have recently proposed a new erythrocyte-based model of study to predict the antiproliferative effects of selected heterocyclic scaffolds. Starting from the metabolic similarity between erythrocytes and cancer cells, we have demonstrated how the metabolic derangement induced by an indolone-based...

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Detalles Bibliográficos
Autores principales: Scala, Angela, Ficarra, Silvana, Russo, Annamaria, Barreca, Davide, Giunta, Elena, Galtieri, Antonio, Grassi, Giovanni, Tellone, Ester
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5019890/
https://www.ncbi.nlm.nih.gov/pubmed/27651854
http://dx.doi.org/10.1155/2016/2104247